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Volume 11, Issue 1, Pages 7-15 (July 2004)

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1 Volume 11, Issue 1, Pages 7-15 (July 2004)
Reversible cholestasis induced by experimental partial obstruction of the bile duct  Emilio A Rodriguez-Garay, Graciela P Rodrı́guez, Gerardo Pisani, Miguel Taborda, Ricardo A Viglianco  Pathophysiology  Volume 11, Issue 1, Pages 7-15 (July 2004) DOI: /j.pathophys

2 Fig. 1 Time course of humoral parameters in rats with partial stenosis of the common bile duct (PS) and in sham rats (C). (A) serum bilirubin (BR); (B) alkaline phosphatase (AP); (C) cholesterol (CH); (D) alanine amino transferase (GPT). Data are mean values±S.E.M. The insets in (A) and (B) show the biexponential decay with time. Pathophysiology  , 7-15DOI: ( /j.pathophys )

3 Fig. 2 Serum tumor necrosis factor alpha (TNF-α) levels in PS second day, C and PS seventh day rat groups. Data represent mean values±S.E.M. (column bar graph) and individual values with the mean (column scatter graph). Pathophysiology  , 7-15DOI: ( /j.pathophys )

4 Fig. 3 Sulfobromophthalein (BSP) and rhodamine B (RB) kinetics. (A) plasma BSP disappearance with time; (B) plasma RB disappearance with time. Data are mean values±S.E.M. Pathophysiology  , 7-15DOI: ( /j.pathophys )

5 Fig. 4 Rate constant values calculated for sulfobromophthalein (BSP) (A) and rhodamine B (RB) (B) in C, PS second day (PS2) and PS seventh day (PS7) rat groups. Data are mean values±S.E.M. For details see Section 2. Pathophysiology  , 7-15DOI: ( /j.pathophys )

6 Fig. 5 The relationship between rate constant a and K1 and between rate constant h and K2 for sulfobromophthalein (BSP) (A) and rhodamine B (RB) (B). Data represent values calculated for C, PS seventh day and PS second day rat groups. For details see Section 2. Pathophysiology  , 7-15DOI: ( /j.pathophys )

7 Fig. 6 The slopes of low decay (K2) after a single i.v. injection of rhodamine B (RB) for C, PS seventh day and PS second day rat groups. For details see Section 2. Pathophysiology  , 7-15DOI: ( /j.pathophys )


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