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56-Year-Old Man With Rash, Abdominal Pain, and Arthralgias
Bettina M. Knoll, MD, PhD, Alfred Valles, MD, Marie C. Hogan, MD, PhD Mayo Clinic Proceedings Volume 82, Issue 6, Pages (June 2007) DOI: / Copyright © 2007 Mayo Foundation for Medical Education and Research Terms and Conditions
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FIGURE 1 Palpable purpuric lesions on the lower extremities of a patient presenting with abdominal pain and arthralgias. The lesions were also distributed on the abdomen and buttocks (not shown). Mayo Clinic Proceedings , DOI: ( / ) Copyright © 2007 Mayo Foundation for Medical Education and Research Terms and Conditions
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FIGURE 2 Immunofluorescence microscopy of kidney biopsy specimen showing granular mesangial staining (2-3+) for IgA in glomeruli. In addition, 3 of 12 glomeruli showed involvement by active necrotizing lesions with epithelial reaction and cellular crescent formation (not shown), and electron microscopy showed mild segmental podocyte foot process effacement. Staining for IgM (1+), C3 (2+), κ light chain (2+), and λ light chain (1+) was positive in the same distribution. Staining for fibrinogen (2+) was noted in scattered glomeruli distributed in a mesangial and capillary loop pattern. Mayo Clinic Proceedings , DOI: ( / ) Copyright © 2007 Mayo Foundation for Medical Education and Research Terms and Conditions
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