1. Endocytic and biosynthetic-secretory pathways
(Ten or more chemically distinct, membrane-enclosed compartments)
Transport vesicles

4. The biosynthetic-secretory and endocytic pathways

9. Various types of coated vesicles
Golgi apparatus
Plasma
ER and
Golgi Cisternae

11. Assembly of a clathrin coat
Coated pits
and vesicles
on the cytosolic
surface of membranes
36 triskelions
12 pentagons
6 hexagons
triskelion
Inner layer
binds adaptins
Freeze-etch

13. GTPases function in vesicle formation
GAP = GTPase Activating Protein
GEF = Guanine Nucleotide Exchange Factor

24. Dynamin pinches of the vesicles
GTPase
Shibire mutant
has coated pits
but no budding off
of synaptic vesicles

36. The entry of enveloped viruses into cells
HIV
Similar to SNAREs