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Volume 126, Issue 5, Pages 1323-1329 (May 2004)
Telangiectatic focal nodular hyperplasia: a variant of hepatocellular adenoma Valerie Paradis, Asmae Benzekri, Delphine Dargère, Ivan Bièche, Ingrid Laurendeau, Valerie Vilgrain, Jacques Belghiti, Michel Vidaud, Claude Degott, Pierre Bedossa Gastroenterology Volume 126, Issue 5, Pages (May 2004) DOI: /j.gastro
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Figure 1 (A and B) Macroscopic view of a case of “telangiectatic FNH” (case TFNH10) (A ) The outer surface of a “telangiectatic” FNH shows several dilated vessels running under the capsula. (B) At cut section, the lesion is well limited, unencapsulated, and displays areas of congestion and hemorrhage. Gastroenterology , DOI: ( /j.gastro )
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Figure 2 Microscopic findings of a case of “telangiectatic FNH“ (case TFNH10) (A ) Few vessels are embedded in extracellular matrix with some inflammatory cells. Note the absence of ductular proliferation. (B) Small isolated arteries are surrounded by regular-sized liver plates. (C ) Congestive areas at low magnification. (D) At higher magnification, some degree of sinusoidal dilatation are observed. Gastroenterology , DOI: ( /j.gastro )
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Figure 3 ANGPT-1/ANGPT-2 mRNA ratio (mean value ± SD) in telangiectatic FNH (TFNH), typical FNH, and adenomas (AD). Gastroenterology , DOI: ( /j.gastro )
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Figure 4 Representative protein profiles of a case of hepatocellular adenoma (AD1), telangiectatic FNH (TFNH 9), and FNH (FNH 5). The spectrum of TFNH match more closely the spectrum of adenoma but differ from those of FNH. Gastroenterology , DOI: ( /j.gastro )
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Figure 5 Clustering analysis of “telangiectatic FNH,” FNH, and hepatocellular adenoma according to protein profling using SELDI-TOF PROTEINCHIP. The dendrogram shows 2 main clusters, 1 with the adenomas, and the other with FNH. All except 1 TFNH (TFNH 3) are included within the cluster of adenomas. Gastroenterology , DOI: ( /j.gastro )
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