1. Volume 15, Issue 7, Pages 1288-1296 (July 2007)
Antisense Oligonucleotide-induced Exon Skipping Across the Human Dystrophin Gene Transcript 
Steve D Wilton, Abbie M Fall, Penny L Harding, Graham McClorey, Catherine Coleman, Susan Fletcher 
Molecular Therapy 
Volume 15, Issue 7, Pages (July 2007)
DOI: /sj.mt
Copyright © 2007 The American Society of Gene Therapy Terms and Conditions

2. Figure 1
AOs to induce removal of dystrophin exons 2–78. The relative size and annealing position of the AO and the intron and exon lengths are indicated.
Molecular Therapy  , DOI: ( /sj.mt )
Copyright © 2007 The American Society of Gene Therapy Terms and Conditions

3. Figure 2
Representative examples of AO-induced dystrophin exon skipping for each class of exon. (a) Type 1 exons are efficiently induced at low AO concentration. (b) Type 2 exons are removed to a lesser extent. (c) Type 3 exons are excluded only at high AO concentrations. (d) Type 4 exons require more than one AO for efficient exclusion or a flanking exon(s) is removed in addition to the target exon.
Molecular Therapy  , DOI: ( /sj.mt )
Copyright © 2007 The American Society of Gene Therapy Terms and Conditions