1. Blood Type 3 Alleles for blood type: A, B, O
A & B are co-dominant (I); O is recessive (i)
Blood type is determined by the proteins found on the red blood cells (RBC)
Phenotype
Genotype A
IAIA or IAi B
IBIB or IBi O ii AB
IAIB

2. Blood Types
Antigens: substances that promote the production of antibodies to kill off cells that may harm the body
RBC Protein Markers(Antigens):
A Allele: Antigen A O Allele: None
B Allele: Antigen B
Type A: antigen A makes anti-B antibodies and kills type B off
Can receive type A or O blood; donate A or AB
Type B: antigen B makes anti-A antibodies and kills type A off
Can receive type B or O blood; donate B or AB

3. Blood Types
Type O: No antigens, makes anti-A and B; kills off type A and B blood
Can receive type O blood; donate to anyone
Type AB: Antigen A & B; NO antibodies produced
Can receive any type of blood; donate to AB only
Review:
Type A: receive A or O blood; donate A or AB
Type B: receive B or O blood; donate B or AB
Type O: receive O blood; donate to A, B, O, or AB
Type AB: receive any blood; donate to AB only

4. Blood Type: Rh Factor Named after Rhesus monkey
Rh factor is based on different protein markers (antigens)
People can be either Rh+ or Rh- (Ex: A+ or A-)
Rh+ is dominant; Rh- is recessive
Most common blood type: O+ & A+; least common: B- & AB-
Type + : Rh antigen does not create Rh antibodies; can receive + or - blood
Type - : No antigen, creates Rh antibodies and kills off + blood; can only receive - ; donate to any

5. Blood Type: Punnett Square
You can do a Punnett Square to determine blood type
Example: Cross a heterozygous type A parent with a type O parent.
Genotypes:
Phenotypes:

6. Blood Type: Punnett Square
Example: Cross a homozygous type B parent with a type AB parent.
Genotypes:
Phenotypes:

7. Blood Type: Punnett Square
Genotypes:
Phenotypes: