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Temperature Dependence of Cerebral Blood Flow for Isolated Regions of the Brain During Selective Cerebral Perfusion in Pigs  Justus T. Strauch, MD, Peter.

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Presentation on theme: "Temperature Dependence of Cerebral Blood Flow for Isolated Regions of the Brain During Selective Cerebral Perfusion in Pigs  Justus T. Strauch, MD, Peter."— Presentation transcript:

1 Temperature Dependence of Cerebral Blood Flow for Isolated Regions of the Brain During Selective Cerebral Perfusion in Pigs  Justus T. Strauch, MD, Peter L. Haldenwang, MD, Katharina Müllem, Miriam Schmalz, Oliver Liakopoulos, MD, Hildegard Christ, Jürgen H. Fischer, MD, Thorsten Wahlers, MD  The Annals of Thoracic Surgery  Volume 88, Issue 5, Pages (November 2009) DOI: /j.athoracsur Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Pigs brain left hemisphere with marked analyzed regions for calculating cerebral blood flow (CBF): (A) pons; (B) cerebellum; (C) cortex; and (D) hippocampus. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Protocol of the experiment, showing time points at which measurements cited in the tables and figures were taken. No microsphere injection for cerebral blood flow (CBF) calculation at time point 7 due to color overlap. (CPB = cardiopulmonary bypass; HCA = hypothermic circulatory arrest; SCP = selective cerebral perfusion.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Overall cerebral blood flow (CBF), cerebral vascular resistance (CVR), and cerebral metabolic rate of oxygen (CMRO2) at different time points during the experiment. All values are shown as mean ± standard error. (SCP = selective cerebral perfusion.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Temperature comparison of cerebral blood flow in absolute values for the four investigated regions of the brain. All values are shown as mean ± standard error. (RBF = regional blood flow; SCP = selective cerebral perfusion.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

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