1. Metabolite predictability is consistent between vaginal and mouse cecal data sets.
Metabolite predictability is consistent between vaginal and mouse cecal data sets. The plot shows the relationship between the level of predictability for each metabolite (measured as the Spearman correlation between pairwise differences in calculated CMP scores and pairwise differences in measured metabolite abundances) in data set 1 (human vaginal microbiome samples) and data set 3 (mouse gut samples). Colors indicate metabolites that are well-predicted in both data sets or anti-predicted in both data sets. Metabolites that are well-predicted in both data sets are enriched for amino acid catabolites, including phenylacetate, spermidine, and beta-alanine.
Cecilia Noecker et al. mSystems 2016; doi: /mSystems