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A Phase II, Open-Label, Randomized Study to Assess the Efficacy and Safety of AZD6244 (ARRY-142886) Versus Pemetrexed in Patients with Non-small Cell.

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Presentation on theme: "A Phase II, Open-Label, Randomized Study to Assess the Efficacy and Safety of AZD6244 (ARRY-142886) Versus Pemetrexed in Patients with Non-small Cell."— Presentation transcript:

1 A Phase II, Open-Label, Randomized Study to Assess the Efficacy and Safety of AZD6244 (ARRY ) Versus Pemetrexed in Patients with Non-small Cell Lung Cancer Who Have Failed One or Two Prior Chemotherapeutic Regimens  John D. Hainsworth, MD, Cristina L. Cebotaru, MD, Vladimir Kanarev, MD, Tudor E. Ciuleanu, MD, Danail Damyanov, MD, PhD, Phillip Stella, MD, Hristo Ganchev, MD, PhD, Gillian Pover, MB, ChB, Clive Morris, MD, Valentina Tzekova, MD  Journal of Thoracic Oncology  Volume 5, Issue 10, Pages (October 2010) DOI: /JTO.0b013e3181e8b3a3 Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 AZD6244 versus pemetrexed study design.
Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181e8b3a3) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Comparison between AZD6244 and pemetrexed in terms of progression-free survival (ITT [intent to treat] population). Journal of Thoracic Oncology 2010 5, DOI: ( /JTO.0b013e3181e8b3a3) Copyright © 2010 International Association for the Study of Lung Cancer Terms and Conditions


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