1. Nucleic Acids
Structure
Cellular Function

2. Nucleic Acids
Structure
Cellular Function

3. Nucleic Acids
Structure
Cellular Function

4. Nucleic Acids
Structure
Cellular Function

5. Central Dogma!

6. Central Dogma!

7. Central Dogma!

8. Proteins
Structure
Cellular Function

9. Proteins
Structure
Cellular Function

10. Proteins
Structure
Cellular Function

11. Proteins
Structure
Cellular Function

12. Proteins
Structure (amino acid)
Cellular Function

13. Proteins
Structure (polypeptides)
Cellular Function

14. Protein – in depth Four structural levels Primary Secondary Tertiary
Quaternary

15. Proteins – in depth

16. Proteins – in depth

17. Proteins – in depth

18. Proteins – in depth

19. Proteins – in depth
“Layers”

20. Protein – in depth
Denaturing
(change in shape/conformation)
Heat pH

21. Try This! (True or Flase?)
1. Primary protein structure is stabilized by peptide bonds between a linear sequence of amino acids.
2. Secondary protein structure is stabilized by hydrogen bonds between R groups on adjacent amino acids.
3. Both primary and tertiary protein structure may be stabilized by covalent bonds.
4. All proteins display primary, secondary, and tertiary levels of protein structure.

22. Try This! (True or Flase?)
1. Primary protein structure is stabilized by peptide bonds between a linear sequence of amino acids.
2. Secondary protein structure is stabilized by hydrogen bonds between R groups on adjacent amino acids.
3. Both primary and tertiary protein structure may be stabilized by covalent bonds.
4. All proteins display primary, secondary, and tertiary levels of protein structure.

23. Try This! (Matching) Levels of protein structure Interactions
1. Primary a. Interactions between R groups
2. Secondary structure b. Hydrogen bonds between constituents of the polypeptide backbone
3. Tertiary structure c. Aggregations between polypeptides
4. Quaternary structure d. Peptide bonds

24. Try This! (Matching) Levels of protein structure Interactions
1. Primary a. Interactions between R groups
2. Secondary structure b. Hydrogen bonds between constituents of the polypeptide backbone
3. Tertiary structure c. Aggregations between polypeptides
4. Quaternary structure d. Peptide bonds

25. Practice! #1-20 p. 36-38 Animations online!
Self Quiz Questions from Campbell (more difficult)
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Concept 1