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Kindr Motors Drive in Meiosis

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1 Kindr Motors Drive in Meiosis
Courtney M. Schroeder, Harmit S. Malik  Cell  Volume 173, Issue 4, Pages (May 2018) DOI: /j.cell Copyright © 2018 Elsevier Inc. Terms and Conditions

2 Figure 1 The Neofunctionalized Motor Kindr Rapidly Moves Knobs along Microtubules into the Megaspore of Maize (A) The Ab10 chromosome contains a block of heterochromatic 180 bp repeats (a “knob”) that is linked to a gene that yields purple kernels, while the wild-type N10 chromosome encodes a yellow marker. The Ab10 knob is genetically tightly linked to tandemly clustered genes named the Kindr complex. The Kindr kinesin localizes to the knob and drives the rapid movement of the Ab10 chromosome toward the minus-end of microtubules (inset). (B) This transmission advantage leads to an excess of purple-colored kernels indicative of meiotic drive, whereas lack of drive leads to Mendelian segregation (equal numbers of yellow and purple kernels). Image credit: R. Kelly Dawe. Cell  , DOI: ( /j.cell ) Copyright © 2018 Elsevier Inc. Terms and Conditions


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