1. Mutations & Genetic Disorders

3. Stumpy, a 4-legged duckling

8. Mutations
Essential Question: How do “mistakes” in genes change the phenotype of an organism?

9. Mutations
mutation: a change in the genetic material

10. Mutations
Point mutation: change in a single point in the DNA

11. Point Mutation

12. Point Mutation

13. Mutations Point mutation: change in a single point in the DNA
substitution: one nucleotide is switched
insertion/deletion: one nucleotide is added/subtracted (also called frameshift mutation)

14. Frameshift Mutation

15. Examples THE FAT CAT ATE THE RAT. Read the sentence below:
What types of mutations are shown below? Which mutation makes more sense?
#1: THE FIT CAT ATE THE RAT.
#2: TEF ATC ATA TET HER AT.
substitution
deletion