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Volume 10, Issue 9, Pages (September 2013)

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1 Volume 10, Issue 9, Pages 1272-1277 (September 2013)
Atrial fibrillation ablation patients have long-term stroke rates similar to patients without atrial fibrillation regardless of CHADS2 score  T. Jared Bunch, MD, Heidi T. May, PhD, MSPH, Tami L. Bair, BS, J. Peter Weiss, MD, Brian G. Crandall, MD, Jeffrey S. Osborn, MD, Charles Mallender, MD, Jeffrey L. Anderson, MD, Brent J. Muhlestein, MD, Donald L. Lappe, MD, John D. Day, MD, FHRS  Heart Rhythm  Volume 10, Issue 9, Pages (September 2013) DOI: /j.hrthm Copyright © 2013 Heart Rhythm Society Terms and Conditions

2 Figure 1 Kaplan-Meier survival estimates are displayed. The survival curves are displayed in 3 groups (atrial fibrillation [AF] no ablation, AF ablation, and no AF) and compared by CHADS2 risk score (0–1, 2–3, ≥4). In all comparisons, patients with AF who did not undergo ablation had early and persistent lower survival free of cerebral vascular accident (stroke) compared to AF ablation patients and patients without AF. AF ablation and no AF patients had similar survival curves. CVA = cerebrovascular accident. Heart Rhythm  , DOI: ( /j.hrthm ) Copyright © 2013 Heart Rhythm Society Terms and Conditions

3 Figure 2 Multivariate hazard ratios (HRs) are displayed for patients with atrial fibrillation (AF) who did not undergo ablation (top 3) and AF patients who underwent ablation (bottom 3) versus patients with no known history of AF. An HR > 1.0 indicates an increased risk of stroke in AF patients not treated with ablation. HRs are displayed by CHADS2 risk scores. Across all categories and subcategories, HR >1.0 are noted in AF ablation patients who did not undergo ablation versus no AF patients. Across all categories and subcategories, HR crossed 1.0 in AF ablation patients versus no AF patients. Heart Rhythm  , DOI: ( /j.hrthm ) Copyright © 2013 Heart Rhythm Society Terms and Conditions

4 Figure 3 Multivariate hazard ratios (HRs) are displayed for patients with atrial fibrillation (AF) who did not undergo ablation versus patients with no known history of AF. An HR > 1.0 indicates an increased risk of stroke in AF patients not treated with ablation. HRs are displayed by age and CHADS2 risk scores. Across all categories and subcategories, HR >1.0 are noted in AF ablation patients who did not undergo ablation. Heart Rhythm  , DOI: ( /j.hrthm ) Copyright © 2013 Heart Rhythm Society Terms and Conditions

5 Figure 4 Multivariate hazard ratios (HRs) are displayed for patients with atrial fibrillation (AF) who underwent ablation versus patients with no known history of AF. An HR > 1.0 indicates an increased risk of stroke in AF patients treated with ablation. HRs are displayed by age and CHADS2 risk scores. Across all categories and subcategories, no significant increase in risk was found for transient ischemic attack or stroke despite the presence of AF in the ablation group. Heart Rhythm  , DOI: ( /j.hrthm ) Copyright © 2013 Heart Rhythm Society Terms and Conditions


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