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NF-κB/Rel/IκB: Implications in gastrointestinal diseases

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Presentation on theme: "NF-κB/Rel/IκB: Implications in gastrointestinal diseases"— Presentation transcript:

1 NF-κB/Rel/IκB: Implications in gastrointestinal diseases
Roland M. Schmid, Guido Adler  Gastroenterology  Volume 118, Issue 6, Pages (June 2000) DOI: /S (00)70374-X Copyright © 2000 American Gastroenterological Association Terms and Conditions

2 Fig. 1 Structure of NF-κB, Rel, and IκB proteins.
Gastroenterology  , DOI: ( /S (00)70374-X) Copyright © 2000 American Gastroenterological Association Terms and Conditions

3 Fig. 2 Different signals converge at a multisubunit kinase complex that contains the IκB kinases α (IKKα) and β (IKKβ). Gastroenterology  , DOI: ( /S (00)70374-X) Copyright © 2000 American Gastroenterological Association Terms and Conditions

4 Fig. 3 The induction of NF-κB/Rel–mediated transcription can be blocked at several levels. Gastroenterology  , DOI: ( /S (00)70374-X) Copyright © 2000 American Gastroenterological Association Terms and Conditions


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