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Fig. 4 Spinally grafted iPSC-NPCs show long-term survival and neuronal and glial differentiation in syngeneic recipient in the absence of immunosuppression.

Published byGioacchino Giannini Modified over 5 years ago

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Presentation on theme: "Fig. 4 Spinally grafted iPSC-NPCs show long-term survival and neuronal and glial differentiation in syngeneic recipient in the absence of immunosuppression."— Presentation transcript:

1 Fig. 4 Spinally grafted iPSC-NPCs show long-term survival and neuronal and glial differentiation in syngeneic recipient in the absence of immunosuppression. Spinally grafted iPSC-NPCs show long-term survival and neuronal and glial differentiation in syngeneic recipient in the absence of immunosuppression. (A) Immunofluorescence staining showing EGFP fluorescence in the core of the graft. (B and C) Immunofluorescence staining showing NF- and GFAP-stained processes in the same areas as in (A). (D to F) Staining with DCX (D), NeuN (E), and NSE (F) in EGFP+ grafts. (G to I) Immunofluorescence staining showing EGFP/NF+ neurites, in areas cranial and caudal to the borders of the graft. (J and K) Costaining of SYN-EGFP+ grafts with VGAT and gephyrin antibodies in the core of the graft. Scale bars, 30 μm (A), 125 μm (B), 10 μm (C), 40 μm (D), 35 μm (E and F), 50 μm (G to I), and 20 μm (J and K). Jan Strnadel et al., Sci Transl Med 2018;10:eaam6651 Published by AAAS

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