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Naloxone lowers cerebrospinal fluid levels of excitatory amino acids after thoracoabdominal aortic surgery  Takashi Kunihara, MD, PhD, Kenji Matsuzaki,

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Presentation on theme: "Naloxone lowers cerebrospinal fluid levels of excitatory amino acids after thoracoabdominal aortic surgery  Takashi Kunihara, MD, PhD, Kenji Matsuzaki,"— Presentation transcript:

1 Naloxone lowers cerebrospinal fluid levels of excitatory amino acids after thoracoabdominal aortic surgery  Takashi Kunihara, MD, PhD, Kenji Matsuzaki, MD, Norihiko Shiiya, MD, PhD, Yasuaki Saijo, MD, PhD, Keishu Yasuda, MD, PhD  Journal of Vascular Surgery  Volume 40, Issue 4, Pages (October 2004) DOI: /j.jvs Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

2 Fig 1 Time course of glutamate levels in the cerebrospinal fluid (CSF) in patients with or without postoperative spinal cord injury. All figure error bars represent standard deviation. All data are presented by percent change from baseline. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

3 Fig 2 Time course of aspartate levels in the cerebrospinal fluid (CSF) in patients with or without postoperative spinal cord injury. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

4 Fig 3 Time course of glycine levels in the cerebrospinal fluid (CSF) in patients with or without postoperative spinal cord injury. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

5 Fig 4 Postoperative maximum levels of CSF EAAs for patients with and without spinal cord injury. All data are presented by percent change from baseline. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

6 Fig 5 Time course of glutamate levels in the cerebrospinal fluid (CSF) in patients given naloxone or not. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

7 Fig 6 Time course of aspartate levels in the cerebrospinal fluid (CSF) in patients given naloxone or not. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

8 Fig 7 Time course of glycine levels in the cerebrospinal fluid (CSF) in patients given naloxone or not. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

9 Fig 8 Postoperative maximum levels of CSF ENAAs compared between patients underwent naloxone-treatment or not. All data are presented by percent change from baseline. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2004 The Society for Vascular Surgery Terms and Conditions

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