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Laurie Seltzer, DO, Michael F

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1 Neurodevelopmental outcomes after neonatal cardiac surgery: Role of cortical isoelectric activity 
Laurie Seltzer, DO, Michael F. Swartz, PhD, Jennifer Kwon, MD, James Burchfiel, PhD, Jill M. Cholette, MD, Hongyue Wang, PhD, Dawn Sweeney, MD, Heather R. Adams, MD, Cecilia Meagher, MD, Ron Angona, CCP, Ronnie Guillet, MD, PhD, George M. Alfieris, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 151, Issue 4, Pages (April 2016) DOI: /j.jtcvs Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Representative EEGs demonstrating: (A) slow and continuous; (B) moderate burst suppression; (C) severe burst suppression; and (D) isoelectric state. F, Frontal; T, temporal; P, parietal; O, occipital; C, cortex. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 A, Mean arterial blood pressure; (B) flow during cardiopulmonary bypass; and (C) temperature at the initiation of each stage of electroencephalogram suppression during the repair of congenital heart disease. MAP, Mean arterial pressure; S/Con, slow and continuous; MBS, moderate burst suppression; SBS, severe burst suppression; IE, isoelectric activity; BSA, body surface area. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Linear regression between the composite Vineland Adaptive Behavior Scale-II score and the duration of an isoelectric state. Circled points represent neonates who received a biventricular cardiac repair. IE, Isoelectricity. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

5 Relationship between the duration of isoelectric activity and neurodevelopmental outcomes.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions


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