1. Challenges and Opportunities in Surgery Research 9 February 2012 Professor Jane Blazeby

4. Made by Srikant Ganesh A good surgeon needs, The eye of an eagle, heart of a lion and hand of a lady 15 th Century English Proverb

5. Spend of the MRC/NIHR on non-surgical & surgical research in 2008/9

6. A paucity of surgical RCTs

8. US Bariatric centres of excellent 2008/9 De Maria E. www.surgicalreview.org Operations for morbid obesity UK National Bariatric surgery registry NBSR www.dendrite.org

9. BAND BYpass BAND BYpass

12. Made by Srikant Ganesh Difficult to select outcomes Technical outcomes Measuring recovery Complications poorly defined

13. Made by Srikant Ganesh Operator expertise & culture

14. MRC Framework

15. Made by Srikant Ganesh Research infrastructure, CTUs & Hubs ConDuCT Edinburgh Midlands Cambridge London Oxford All-Ireland Northwest

17. The lady you saw in clinic Monday wants to be randomized! ! Its the way I talk to them young Jedi.

18. Trainee-led Surgical Research Collaboratives - Lessons learnt from the ROSSINI trial Mr Thomas Pinkney

19. ROSSINI Reduction Of Surgical Site Infection using a Novel Intervention A randomised controlled trial of a wound-edge protection device to reduce surgical site infection Inclusion:All patients undergoing laparotomy Exclusion:Laparoscopic-assisted surgery Blinded wound reviews Pre-discharge (5-7 days) & at 30-33 days Funded by NIHR Research for Patient Benefit programme

21. Made by Srikant Ganesh Other research collaboratives London – LSRG South West – SPARCS Mersey – MERGS Yorkshire Kent/Maidstone Trent Cardiothoracic collaborative Yorkshire orthopaedic group

22. Made by Srikant Ganesh Opportunities Feasibility work/studies (RfPB, HTA) Program research, RCTs (NIHR & HTA) Clinical academic pathways, NIHR PhDs.

23. Where theres a will theres a way

24. Thank you 9 February 2012