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CAIA is attenuated in Nrdc – / – mice.

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1 CAIA is attenuated in Nrdc – / – mice.
CAIA is attenuated in Nrdc–/– mice. (A) Photographs of the hind paws 4 days and 7 days after the induction of CAIA. Upper panels, wild-type (WT); lower panels, Nrdc–/– mice. (B) Arthritis score (upper) and ankle thickness (lower) were measured daily after the induction of CAIA. n=5 per genotype (mean ± SEM). *p<0.05; **p<0.01, Welch’s t-test. (C) H&E staining of the ankle joints 14 days after the induction of CAIA in WT (upper panels) and Nrdc–/– (lower panels) mice. Scale bars: 500 µm in the 40× magnification and 200 µm in the 100× magnification. Symbols in the 100x magnification images: arrow, bone erosion; arrow head, cartilage erosion; *, hypertrophic synovium. Takayuki Fujii et al. RMD Open 2017;3:e000436 Copyright © BMJ Publishing Group & EULAR. All rights reserved.

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