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Alport syndrome–like basement membrane changes in frasier syndrome: an electron microscopy study  Shu-ichi Ito, MD, Hiroshi Hataya, MD, Masahiro Ikeda,

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Presentation on theme: "Alport syndrome–like basement membrane changes in frasier syndrome: an electron microscopy study  Shu-ichi Ito, MD, Hiroshi Hataya, MD, Masahiro Ikeda,"— Presentation transcript:

1 Alport syndrome–like basement membrane changes in frasier syndrome: an electron microscopy study 
Shu-ichi Ito, MD, Hiroshi Hataya, MD, Masahiro Ikeda, MD, Ayako Takata, MD, Haruhito Kikuchi, MD, Jun-ichi Hata, MD, Yukihiko Morikawa, MD, Sadao Kawamura, MD, Masataka Honda, MD  American Journal of Kidney Diseases  Volume 41, Issue 5, Pages (May 2003) DOI: /S (03) Copyright © Terms and Conditions

2 Fig 1 (A) Photomicrograph shows mild mesangial proliferation in the glomeruli (Periodic acid methanamine [PAM] stain, original magnification × 300). (B) Electron micrograph shows widespread thinning (arrow). (Original magnification × 8,000.) (C) Electron micrograph shows splitting and lamellation (arrowheads) of the glomerular basement membrane. (Original magnification × 10,000.) American Journal of Kidney Diseases  , DOI: ( /S (03) ) Copyright © Terms and Conditions

3 Fig 2 (A) Photomicrograph shows mild mesangial proliferation and focal segmental sclerotic lesions in the glomeruli. (PAM stain, original magnification × 300.) (B) Electron micrograph shows widespread thinning of the basement membrane and effacement of foot processus of podocytes (open arrow), wrinkling (arrowhead), splitting, and lamellation (arrow) of the basement membrane (original magnification × 6,000.) American Journal of Kidney Diseases  , DOI: ( /S (03) ) Copyright © Terms and Conditions


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