1. Ketamine, but not propofol, anaesthesia is regulated by metabotropic glutamate 5 receptors 
Sou J.-H. , Chan M.-H. , Chen H.-H.  
British Journal of Anaesthesia 
Volume 96, Issue 5, Pages (May 2006)
DOI: /bja/ael046
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
Dose-dependent effect of DHPG and CHPG on ketamine-induced anaesthesia. Mice were pretreated with ACSF, DHPG (5 and 50 nmol, i.c.v.) (a) or CHPG (0.5, 2.5 and 5 nmol, i.c.v.) (b) and the duration of LORR was recorded after administration of ketamine (120 mg kg−1, i.p.). All values are expressed as the mean (sem) (n=6). One-way anova: F(2,15)=7.098, P= for DHPG; F(3,20)=18.91, P< for CHPG; *P<0.05, **P<0.01, ***P<0.001 compared with the vehicle control (Student–Newman–Keuls test).
British Journal of Anaesthesia  , DOI: ( /bja/ael046)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Dose-dependent effect of CPCCOEt and MPEP on ketamine-induced anaesthesia. Mice were pretreated with ACSF, CPCCOEt (5, 50 and 500 nmol, i.c.v.) (a) or MPEP (50, 100 and 200 nmol, i.c.v.) (b) and the duration of LORR was recorded after administration of ketamine (120 mg kg−1, i.p.). All values are expressed as the mean (sem) (n=6). One-way anova: F(3,20)=2.762, P=0.07 for CPCCOEt; F(3,20)=13.77, P< for MPEP. ***P<0.001 compared with the vehicle control (Student–Newman–Keuls test).
British Journal of Anaesthesia  , DOI: ( /bja/ael046)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

4. Fig 3
Dose-dependent effect of DHPG and CHPG on propofol-induced anaesthesia. Mice were pretreated with ACSF, DHPG (5 and 50 nmol, i.c.v.) (a) or CHPG (5 and 50 nmol, i.c.v.) (b) and the duration of LORR was recorded after administration of propofol (140 mg kg−1, i.p.). All values are expressed as the mean (sem) (n=6). One-way anova: F(2,15)=0.476, P=0.63 for DHPG; F(2,15)=0.727, P=0.499 for CHPG.
British Journal of Anaesthesia  , DOI: ( /bja/ael046)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions

5. Fig 4
Dose-dependent effect of CPCCOEt and MPEP on propofol-induced anaesthesia. Mice were pretreated with ACSF, CPCCOEt (50 and 500 nmol, i.c.v.) (a) or MPEP (50 and 200 nmol, i.c.v.) (b) and the duration of LORR was recorded after administration of propofol (140 mg kg−1, i.p.). All values are expressed as the mean (sem) (n=6). One-way anova: F(2,15)=0.133, P=0.87 for CPCCOEt; F(2,15)=0.542, P=0.59 for MPEP.
British Journal of Anaesthesia  , DOI: ( /bja/ael046)
Copyright © 2006 British Journal of Anaesthesia Terms and Conditions