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IIV induces CD21hiCD27+ and CD21loCD27+ influenza-specific B cells

Published byΆφροδίτη Αγγελίδης Modified over 5 years ago

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Presentation on theme: "IIV induces CD21hiCD27+ and CD21loCD27+ influenza-specific B cells"— Presentation transcript:

1 Fig. 3 IIV induces CD21hiCD27+ and CD21loCD27+ influenza-specific B cells.
IIV induces CD21hiCD27+ and CD21loCD27+ influenza-specific B cells. (A) Numbers of rHA+IgD− B cells before and after vaccination. Representative FACS plots of rHA+ B cells after vaccination. (B) Numbers of rHA+ B cells per milliliter of blood for each vaccine component. (C) Representative FACS plots and (D) frequency of CD27+CD20−rHA+ B cells before and after vaccination. (E) Numbers of isotype-specific rHA+ B cells. (F) Representative FACS plots for d0 and d14. (G) Numbers of CD21hiCD27+ and CD21loCD27+ IgG+rHA+ B cells. (E and G) Pooled data from 2015 and 2016 cohorts (n = 42). Bars indicate the median. Statistical significance for changes from baseline was determined using Wilcoxon matched-pairs signed-rank test (*P < 0.05, **P < 0.005, ***P < 0.001, ****P < ). Marios Koutsakos et al., Sci Transl Med 2018;10:eaan8405 Published by AAAS

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