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Problem Set – Litterature

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Presentation on theme: "Problem Set – Litterature"— Presentation transcript:

1 Problem Set – Litterature
A presentation by Guillaume Pelletier on October 27th 2009

2 Question #1: [1,4]-Conjugated Addition of an Organo-Rhodium speicies.
(a) Wuitschik, G.; Rogers-Evans, M.; Müller, K.; Fisher, H.; Wagner, B.; Schuler, F.; Polonchuk, L.; Carreira, E. M. Angew. Chem. Int. Ed. 2006, 45, (b) Fagnou, K.; Lautens, M. Chem. Rev. 2003, 103,

3 Question #1: [1,4]-Conjugated Addition of an Organo-Rhodium speicies.
(a) Wuitschik, G.; Rogers-Evans, M.; Müller, K.; Fisher, H.; Wagner, B.; Schuler, F.; Polonchuk, L.; Carreira, E. M. Angew. Chem. Int. Ed. 2006, 45, (b) Fagnou, K.; Lautens, M. Chem. Rev. 2003, 103,

4 Question #2: Formation of an [1,2]-trans-Aminoalcohol from an Oxetane.
Bach, T.; Schröder, J. J. Org. Chem. 1999, 64,

5 Question #2: Formation of an [1,2]-trans-Aminoalcohol from an Oxetane.
Bach, T.; Schröder, J. J. Org. Chem. 1999, 64,

6 Question #3: Oxetane by fragmentation
(a) Marshall, J. A.; Arrington, J. P. J. Org. Chem. 1971, 36, (b) Waters, J. A.; Witkop, B. J. Org. Chem. J. Org. Chem. 1969, 34, 3774.

7 Question #3: Oxetane by fragmentation
Marshall, J. A.; Arrington, J. P. J. Org. Chem. 1971, 36, (b) Waters, J. A.; Witkop, B. J. Org. Chem. J. Org. Chem. 1969, 34, 3774. (c) Moran, J.; Dornan, P.; Beauchemin, A. M. Org. Lett. 2007, 9,

8 Question #3: Oxetane by fragmentation
Marshall, J. A.; Arrington, J. P. J. Org. Chem. 1971, 36, (b) Waters, J. A.; Witkop, B. J. Org. Chem. J. Org. Chem. 1969, 34, 3774. (c) Moran, J.; Dornan, P.; Beauchemin, A. M. Org. Lett. 2007, 9,

9 Question #3: Oxetane by fragmentation
Marshall, J. A.; Arrington, J. P. J. Org. Chem. 1971, 36, (b) Waters, J. A.; Witkop, B. J. Org. Chem. J. Org. Chem. 1969, 34, 3774. (c) Moran, J.; Dornan, P.; Beauchemin, A. M. Org. Lett. 2007, 9,

10 Question #4: Allylic strain
Bach, T.; Jödicke, K.; Kather, K.; Frölich, R. J. Am. Chem. Soc. 1997, 119,

11 Question #4: Allylic strain
Bach, T.; Jödicke, K.; Kather, K.; Frölich, R. J. Am. Chem. Soc. 1997, 119,

12 Question #5 : « Norrish type 2-like » fragmentation
Booker-Milburn, K. I.; Baker, J. R.; Bruce, I. Org. Lett. 2004, 6,

13 Question #5 : « Norrish type 2-like » fragmentation
Booker-Milburn, K. I.; Baker, J. R.; Bruce, I. Org. Lett. 2004, 6,


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