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Giant Solitary Fibrous Tumor of the Epicardium Causing Reversible Heart Failure
Giacomo Bianchi, MD, Matteo Ferrarini, MD, Marco Matteucci, PhD, Angelo Monteleone, MD, Giovanni Donato Aquaro, MD, Claudio Passino, MD, PhD, Angela Pucci, MD, PhD, Mattia Glauber, MD The Annals of Thoracic Surgery Volume 96, Issue 2, Pages e49-e51 (August 2013) DOI: /j.athoracsur Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions
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Fig 1 (A, B, C) Computed tomographic scans showing intrapericardial giant solitary fibrous tumor and its relationships with the surrounding structures. (A) Inferior wall of the heart is displaced and distortion of mitral valve is evident in the left ventricle inflow tract; the arterial feeders originate from the posterior descending artery (B, arrow) and from the circumflex artery (C, arrow). (D) gross features of the tumor after operation (arrow: vessels). The Annals of Thoracic Surgery , e49-e51DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions
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Fig 2 Cardiovascular magnetic resonance images showing (A) severe distortion of ventricle and mitral valve (two-chamber view of left ventricle) and (B) dishomogeneity in the inner core of the mass (short-axis view of tumor and of diaphragmatic portion of heart). The Annals of Thoracic Surgery , e49-e51DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions
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Fig 3 Microscopic features of the tumor, showing solid proliferation of monomorphic spindle-shaped fibroblastic cells intermingled with broad collagenous fibers. (A) Hematoxylin and eosin; ×20. (B) Masson's trichrome; ×40. The spindle cells display (C) diffuse Bcl-2 immunostaining (×40) and (D) intense immunoreactivity for CD34. (Immunoperoxidase; ×40.) The Annals of Thoracic Surgery , e49-e51DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions
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