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Fabry Disease With Aortic Regurgitation
Soojeong Choi, MD, Haesun Seo, MD, Mooyong Park, MD, Jinkuk Kim, MD, Seungduk Hwang, MD, Kaewon Kwon, MD, Kyun Her, MD, Yongsoon Won, MD The Annals of Thoracic Surgery Volume 87, Issue 2, Pages (February 2009) DOI: /j.athoracsur Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions
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Fig 1 (A) The kidney biopsy under light microscopy shows glomeruli with enlarged, vacuolated visceral epithelial cells. (Hematoxylin & eosin; ×400.) (B) An electron microscopy reveals podocytes filled with myelin bodies of variable size. (Uranyl acetate and lead citrate; ×1500). The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions
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Fig 2 Transthoracic echocardiographic image. (A) Two-dimensional echocardiogram shows enlarged left ventricle with thickened aortic and mitral valve. (B) Color Doppler shows severe aortic regurgitant jet flow. The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions
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Fig 3 (A) The heart biopsy under light microscopy shows mild fibrosis, chronic inflammation, and vacuolar changes. (Hematoxylin & eosin; ×200, myocardium). (B) Electron microscope image of a treated Fabry myocyte. Normal appearing myofibrils are present at the cell periphery. The middle of the cell is vacuolated (electron microscopy, original magnification; ×3,000). The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions
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