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Schematic depiction of CTC processing methods.
Schematic depiction of CTC processing methods. Enrichment techniques are necessary to separate the extremely rare CTCs from peripheral blood cells (erythrocytes and leukocytes). Identification of CTCs is then performed generally through immunofluorescence or RT-PCR techniques. RBC, red blood cells; WBC, white blood cells. Reproduced from Arya et al. (120) by permission of the Royal Society of Chemistry. Access the most recent version of this article at: Timothy A. Yap et al. Clin Cancer Res 2014;20: ©2014 by American Association for Cancer Research
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