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Published byΘυία Αλεξίου Modified over 5 years ago
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Targeting the IL17 Pathway for the Prevention of Graft-Versus-Host Disease
Anniek B. van der Waart, Walter J.F.M. van der Velden, Nicole M. Blijlevens, Harry Dolstra Biology of Blood and Marrow Transplantation Volume 20, Issue 6, Pages (June 2014) DOI: /j.bbmt Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions
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Figure 1 Th/Tc17 cell differentiation. Cytokines produced by dendritic cells differentiate naive T cells (Tn) towards Th/Tc17 cells. DC indicates dendritic cell; Tn, naive T cell; Th/Tc, helper T cell/cytotoxic T cell. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions
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Figure 2 Th/Tc17 pathway involved in GVHD and its potential targets. TBI indicates total body irradiation; F-actin, filament actin; DNGR1, DC NK lectin group receptor; DC, dendritic cell. DAMP, danger-associated molecular patterns; PAMP, pathogen-associated molecular patterns, Th/Tc, helper T cell/cytotoxic T cell. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions
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