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A Novel Large-Animal Model of Peripheral Arterial Disease

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Presentation on theme: "A Novel Large-Animal Model of Peripheral Arterial Disease"— Presentation transcript:

1 A Novel Large-Animal Model of Peripheral Arterial Disease
Chandler A. Long, Michael Sweet, Tatiana Chadid, Panagiotis Koutakis, Traci Goodchild, David Lefer, Iraklis Pipinos, George Casale, W. Robert Taylor, Luke Brewster  Journal of Vascular Surgery  Volume 63, Issue 1, Pages (January 2016) DOI: /j.jvs Copyright © Terms and Conditions

2 Fig 1 Arteriogenesis in the Yorkshire but not the Ossabaw swine. A, Preocclusion aortogram with equal sized IIA (blue double arrows). B, Arteriogenesis of right compared with left internal iliac artery (blue double arrows). C, Robust angiogenesis in Yorkshire aortogram but not in the (D) Ossabaw swine, which have metabolic syndrome. NS, Not significant; ∗P < .01. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © Terms and Conditions

3 Fig 2 Graphic representation of hind limb index (HLI) and duplex velocity over time. Sustained ischemia in Yorkshire (A) HLI and (B) duplex velocities, but there is recovery over time that correlated with increasing systolic velocity. ∗P < .05. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © Terms and Conditions

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