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A Novel Methionine-53-Valine Mutation of p16 in a Hereditary Melanoma Kindred
Guang Yang, Kristin Baker Niendorf, Hensin Tsao Journal of Investigative Dermatology Volume 123, Issue 3, Pages (September 2004) DOI: /j X x Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 1 Met53Val Pedigree and Mutation. (A). The patient's pedigree. The proband is indicated by the arrowhead. Abbreviations for cancers include MEL, melanoma; BR, breast; LY, lymphoma. Melanomas are shaded black on the right upper quadrant; other cancers are shaded gray in various quadrants. Mutation status: (+) carriers, (-) noncarriers. (B). The G/A transition at nt167 (starting from the first ATG of the p16 transcript) is indicated by the blue arrow. Journal of Investigative Dermatology , DOI: ( /j X x) Copyright © 2004 The Society for Investigative Dermatology, Inc Terms and Conditions
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