1. SAS/Graph to help data Dose/Concentration consistency review
Patrick Lupien, Principal Statistical Programmer
Berlin, October 20, 2010

2. SAS/Graph Agenda Why a graph macro?
Plot 1 : Dose vs concentration time
Plot 2 : Overall concentration
Plot 3 : Subject profile
More options
Questions
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3. Help validation process Check data quality and data issues
Why a graph macro
Help validation process
Check data quality and data issues
Find outlier
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4. Macro prerequisite Data must be merged in one dataset
A time column must exist
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5. Plot 1 : Dose vs concentration time
Show dose and concentration date/time relation
Ease finding missing dose or incorrect event time
Display number of sample for each subject
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6. Plot 1 : Dose vs concentration time
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7. Plot 1 : Dose vs concentration time
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8. Plot 1 : Dose vs concentration time
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9. Plot 1 : Dose vs concentration time
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10. Plot 1 : Dose vs concentration time Extract of SAS code
Column _msBreak limit the number of subject per page
Format _msgrph display suject and number of samples
Both series overlap each other but use different symbol
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11. Plot 2 : Overall concentration
Help find outlier
Ensure concentration levels are consistent
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12. Plot 2 : Overall concentration
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13. Plot 2 : Overall concentration
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14. Plot 2 : Overall concentration SAS code
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15. Plot 3 : Subject profile Allow detail review of all subjects
Help find patterns
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16. Plot 3 : Subject profile
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17. Plot 3 : Subject profile SAS code
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18. Global macro options Create only some of the graphs
Multiple compartements, separated by a “/“
Allow subset
Allow group by option
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19. Questions ?
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