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Continuous Subcutaneous Administration of High-Dose Salmon Calcitonin in Bone Metastasis  Kyriaki Mystakidou, MD, PhD, Sofia Befon, MD, Kostas Hondros,

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Presentation on theme: "Continuous Subcutaneous Administration of High-Dose Salmon Calcitonin in Bone Metastasis  Kyriaki Mystakidou, MD, PhD, Sofia Befon, MD, Kostas Hondros,"— Presentation transcript:

1 Continuous Subcutaneous Administration of High-Dose Salmon Calcitonin in Bone Metastasis 
Kyriaki Mystakidou, MD, PhD, Sofia Befon, MD, Kostas Hondros, PhD, Evagelia Kouskouni, MD, PhD, Labros Vlahos, MD, PhD  Journal of Pain and Symptom Management  Volume 18, Issue 5, Pages (November 1999) DOI: /S (99)

2 Fig. 1 Pain score reduction during the study time period
Journal of Pain and Symptom Management  , DOI: ( /S (99) )

3 Fig. 2 Beta-endorphin plasma level variation vs. time
Journal of Pain and Symptom Management  , DOI: ( /S (99) )

4 Fig. 3 Twelve-hour change of beta-endorphin plasma levels—pain score
Journal of Pain and Symptom Management  , DOI: ( /S (99) )

5 Fig. 4 Twenty-four hour change of beta-endorphin plasma levels—pain score Journal of Pain and Symptom Management  , DOI: ( /S (99) )

6 Fig. 5 Variation of calcium blood levels over time. *Indicates statistically significant differences between all study time intervals and base line comparisons. **Indicates statistically significant differences between all study time interval comparisons Journal of Pain and Symptom Management  , DOI: ( /S (99) )

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