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Volume 11, Issue 4, Pages (May 2005)

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Presentation on theme: "Volume 11, Issue 4, Pages (May 2005)"— Presentation transcript:

1 Volume 11, Issue 4, Pages 209-213 (May 2005)
Erythrocyte membrane fluidity and haemoglobin haemoporphyrin conformation: features revealed in patients with heart failure  O.V. Rodnenkov, O.G. Luneva, N.A. Ulyanova, G.V. Maksimov, A.B. Rubin, S.N. Orlov, E.I. Chazov  Pathophysiology  Volume 11, Issue 4, Pages (May 2005) DOI: /j.pathophys Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Representative EPR spectra of erythrocytes isolated from a healthy donor and labeled with 5-DS (a) or 16-DS (b). Pathophysiology  , DOI: ( /j.pathophys ) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Representative Raman spectrum of blood from a healthy donor. Combination scatter bands with maximum intensity at 1355, 1375, 1564, 1580, 1618 and 1668cm−1 are indicated by Roman numerals. Pathophysiology  , DOI: ( /j.pathophys ) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

4 Fig. 3 Schematic representation of Hb–ligand complexes with O2 and NO. 1: globin, 2: porphyrin, 3–7: coordinating bonds involved in Fe2+, porphyrin, globin and ligand interactions. (a) Ligand-free Hb; (b) oxyhaemoglobin; (c) Hb–NO complex with preserved Fe2+-globin bond; (d) Hb–NO complex with cleaved Fe2+-globin bond. Pathophysiology  , DOI: ( /j.pathophys ) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions


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