1. What the asthma end points we know and love do and do not tell us
Allan T. Luskin, MD 
Journal of Allergy and Clinical Immunology 
Volume 115, Issue 4, Pages S539-S545 (April 2005)
DOI: /j.jaci
Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

2. Fig 1
There is an approximate 40% divergence comparing positive or lack of response with lung function and symptoms as outcomes. Reprinted with permission from Shingo et al. Copyright © 2001 European Respiratory Society Journals Ltd. All rights reserved.2
Journal of Allergy and Clinical Immunology  , S539-S545DOI: ( /j.jaci )
Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

3. Fig 2
There is high correlation between measures of lung function (FEV1 and peak expiratory flow rate) and between daytime symptom scores and β-agonist use but only marginal negative correlation between lung function and daytime symptom scores and between lung function and β-agonist use. PEFR, Peak expiratory flow rate; DSS, daytime symptom score. Reprinted with permission from Zhang et al. Copyright © 2002 European Respiratory Society Journals Ltd. All rights reserved.6
Journal of Allergy and Clinical Immunology  , S539-S545DOI: ( /j.jaci )
Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

4. Fig 3
Patients' perception of severity correlates modestly with guideline severity. There are large populations with striking divergence of severity categorization. NAEPP, National Asthma Education and Prevention Program. Reprinted with permission from Asthma in America.14
Journal of Allergy and Clinical Immunology  , S539-S545DOI: ( /j.jaci )
Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions

5. Fig 4
The relative risk ratio of hospitalization for asthma in a group of subjects with moderate-to-severe asthma is affected by certain comorbidities, particularly gastrointestinal diagnosis and depression. G-I, Gastrointestinal. Reprinted with permission from Sullivan et al.20
Journal of Allergy and Clinical Immunology  , S539-S545DOI: ( /j.jaci )
Copyright © 2005 American Academy of Allergy, Asthma and Immunology Terms and Conditions