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Investigations in generalized osteoarthritis

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1 Investigations in generalized osteoarthritis
Investigations in generalized osteoarthritis. Part 1: Genetic study of Heberden's nodes  U. Irlenbusch, M.D., Th. Schäller  Osteoarthritis and Cartilage  Volume 14, Issue 5, Pages (May 2006) DOI: /j.joca Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

2 Fig. 1 Fictitious clan table of 93 index cases with 156 descendants: ♦ total, □ male, and ○ female. White signs: healthy till now. Black signs: manifest affected. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

3 Fig. 2 Combination square in monomeric inheritance for heterozygous–homozygous parents. H=gene for trait Heberden's arthritis and h=normal gene. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

4 Fig. 3 Age pattern of the daughters of the index cases.
Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions


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