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Differential modulation of interleukin‐6 and interleukin‐10 by diclofenac in patients undergoing major surgery  A.M. Mahdy, H.F. Galley, M.A. Abdel‐Wahed,

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Presentation on theme: "Differential modulation of interleukin‐6 and interleukin‐10 by diclofenac in patients undergoing major surgery  A.M. Mahdy, H.F. Galley, M.A. Abdel‐Wahed,"— Presentation transcript:

1 Differential modulation of interleukin‐6 and interleukin‐10 by diclofenac in patients undergoing major surgery  A.M. Mahdy, H.F. Galley, M.A. Abdel‐Wahed, K.F. El‐Korny, S.A. Sheta, N.R. Webster  British Journal of Anaesthesia  Volume 88, Issue 6, Pages (June 2002) DOI: /bja/ Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

2 Fig 1 Changes in circulating IL‐6 concentrations during major urological surgery in patients treated with diclofenac (P<0.0001, Friedman analysis of variance) and those treated with placebo (P<0.0001, Friedman analysis of variance). Box and whisker plot showing median, 25th and 75th percentiles and range. **P<0.001 compared with basal (before surgery). British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

3 Fig 2 Changes in circulating IL‐10 concentrations during major urological surgery in patients treated with diclofenac (P<0.0001, Friedman analysis of variance) and those treated with placebo (P<0.0001, Friedman analysis of variance). Box and whisker plot showing median, 25th and 75th percentiles and range. *P<0.01 and **P<0.001 compared with basal (before surgery). British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions

4 Fig 3 Changes in circulating cortisol concentrations during major urological surgery in patients treated with diclofenac (P<0.0001, Friedman analysis of variance) and those treated with placebo (P<0.0001, Friedman analysis of variance). Box and whisker plot showing median, 25th and 75th percentiles and range. *P<0.01 and **P<0.001 compared with basal (before surgery). British Journal of Anaesthesia  , DOI: ( /bja/ ) Copyright © 2002 British Journal of Anaesthesia Terms and Conditions


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