1. Vitiligo and chromoblastomycosis.
Vitiligo and chromoblastomycosis. (A) A 62-year-old Brazilian man presented with a 10-year history of a slow-growing plaque lesion, which started as a small nodule near his navel and spread centrifugally until it reached 30 cm in diameter. Concomitantly, he noted the presence of interwoven achromic patches, which extended to other regions of his skin after 5 years of having the disease restricted to the abdominal area. (B) A skin scraping from the plaque lesion revealed the presence of muriform cells. (C and D) After 3 weeks of culture in Mycosel, a grayish colony grew (C), and micromorphology depicted Fonsecaea pedrosoi structures (D). (E and F) An association of CBM and vitiligo has not been reported, but the presence of antimelanin antibodies in CBM patients is known. Most of the cases that were treated with itraconazole were healed, leaving an achromic patch (F) in place of the previous verrucous/plaque lesions (E). This patient developed vitiligo after CBM, which could be related to the presence of antimelanin antibodies.
Flavio Queiroz-Telles et al. Clin. Microbiol. Rev. 2017; doi: /CMR