1. TSG-6 activity as a novel biomarker of progression in knee osteoarthritis 
H.-G. Wisniewski, E. Colón, V. Liublinska, R.J. Karia, T.V. Stabler, M. Attur, S.B. Abramson, P.A. Band, V.B. Kraus 
Osteoarthritis and Cartilage 
Volume 22, Issue 2, Pages (February 2014)
DOI: /j.joca
Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

2. Fig. 1
TSG-6 activities in synovial fluid by knee OA progression status. Shown is a box plot of TSG-6 activities in four OA outcome categories: NP (N = 60), OST only progressors (OST+/JSN−, N = 49), JSN progressors (OST+/JSN+, N = 12), and TKA progressors (N = 11), as indicated. The boxes indicate 10%, 25%, 75% and 90% quantiles and the median for each outcome group. The line indicates the mean of the whole sample (N = 132, mean = 9.85 u/ml).
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions

3. Fig. 2
ROC curve for the TSG-6 activity assay and the outcome TKA vs non-TKA. The area under the curve is A TSG-6 cut-off point of 13.3 u/ml, determined by Youden's index, yielded a sensitivity of 0.91 and a specificity of 0.82.
Osteoarthritis and Cartilage  , DOI: ( /j.joca )
Copyright © 2013 Osteoarthritis Research Society International Terms and Conditions