1. GeneGoTM-based signaling pathway annotations of proteins identified in CD56+ NK cell subsets.
GeneGoTM-based signaling pathway annotations of proteins identified in CD56+ NK cell subsets.A, The Venn diagram depicts the numbers of identified proteins in CD56+ NK cells subsets common proteins were identified in CD56dim/bright and CD57+/− NK cells. 13 proteins were unique in CD56dim/bright NK cells and 54 in CD57+/− NK cells. B, Data sets (all proteins, n = 5, median) were loaded into GeneGoTM. This program assigns proteins to certain pathways by computing a statistical relevance value (negative log p value). The negative log p value depicts the ratio of proteins identified in this study and proteins known to be present within this pathway. Hierarchical order was defined by CD57− NK cell subsets. Numbers depict the order within the CD56bright/dim GeneGoTM analysis.
Maxi Scheiter et al. Mol Cell Proteomics 2013;12:
© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.