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The Clinical Implications of Cytochrome P450 Interactions With Opioids and Strategies for Pain Management  Michael J. Brennan, MD  Journal of Pain and.

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Presentation on theme: "The Clinical Implications of Cytochrome P450 Interactions With Opioids and Strategies for Pain Management  Michael J. Brennan, MD  Journal of Pain and."— Presentation transcript:

1 The Clinical Implications of Cytochrome P450 Interactions With Opioids and Strategies for Pain Management  Michael J. Brennan, MD  Journal of Pain and Symptom Management  Volume 44, Issue 6, Pages S15-S22 (December 2012) DOI: /j.jpainsymman Copyright © Terms and Conditions

2 Fig. 1 Patient concerns about the health system in a national survey by the American Society of Health-System Pharmacists.15 Journal of Pain and Symptom Management  , S15-S22DOI: ( /j.jpainsymman ) Copyright © Terms and Conditions

3 Fig. 2 Example of the metabolism of opioids.17
Reprinted with permission from Gourlay DL, Heit HA, Caplan YH. Urine drug testing in clinical practice: the art and science of patient care. Stamford, CT: PharmaCom Group, Inc., 2010. Journal of Pain and Symptom Management  , S15-S22DOI: ( /j.jpainsymman ) Copyright © Terms and Conditions


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