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Volume 62, Issue 6, Pages 1455-1456 (June 2015)
Erratum to “Inhibition of fibronectin deposition improves experimental liver fibrosis” [J Hepatol 2015;62:625–633] Eva Altrock, Carla Sens, Carina Wuerfel, Matthaeus Vasel, Nina Kawelke, Steven Dooley, Jane Sottile, Inaam A. Nakchbandi Journal of Hepatology Volume 62, Issue 6, Pages (June 2015) DOI: /j.jhep Copyright © 2015 European Association for the Study of the Liver Terms and Conditions
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Fig. 4 pUR4 does not affect Kupffer cells or hepatic stellate cells in vivo in the CCl4/parallel model. (A) Fibrosis was induced using CCl4 for 42days. Parallel to that, mice received daily pUR4 or CT-peptide for the last 10days (CCl4/parallel). (B) pUR4 does not affect the number of F4/80+ cells. Left Panel shows stained sections and the right panel the quantification. TGF-β mRNA (C), TNF-α mRNA (D), and total TGF-β protein expression (E) in liver tissue were not significantly affected by pUR4 administration. (F) The number of α-SMA-expressing cells is not affected by pUR4-treatment. Panel shows stained sections. (G) Quantification of cells shown in (F). (H) α-SMA as determined by Western blotting was not affected by pUR4-treatment either. Densitometry is shown on the left and a representative blot on the right. (I) α-SMA mRNA-expression was not affected by pUR4-treatment. Bars represent 100μm. n=4–6/group. Journal of Hepatology , DOI: ( /j.jhep ) Copyright © 2015 European Association for the Study of the Liver Terms and Conditions
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