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Effect of VKORC1 Haplotype Combination on Clinical Warfarin Dose - Common haplotypes (H1, H2, H7, H8, and H9) were clustered with use of the UPGMA method.

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Presentation on theme: "Effect of VKORC1 Haplotype Combination on Clinical Warfarin Dose - Common haplotypes (H1, H2, H7, H8, and H9) were clustered with use of the UPGMA method."— Presentation transcript:

1 Effect of VKORC1 Haplotype Combination on Clinical Warfarin Dose - Common haplotypes (H1, H2, H7, H8, and H9) were clustered with use of the UPGMA method M.J. Rieder et al. N Engl J Med 2005;352:

2 Effect of VKORC1 Haplotype Combination on Clinical Warfarin Dose - Primary Population
M.J. Rieder et al. N Engl J Med 2005;352:

3 Effect of VKORC1 Haplotype Combination on Clinical Warfarin Dose - Replication Population
M.J. Rieder et al. N Engl J Med 2005;352:

4 VKORC1 Haplotype Frequency and Effect on Warfarin Dose among 186 European-American Patients
M.J. Rieder et al. N Engl J Med 2005;352:

5 Distribution of VKORC1 Haplotypes in European-American, African-American, and Asian-American Populations M.J. Rieder et al. N Engl J Med 2005;352:

6 Correlation between VKORC1 Haplotype Groups and VKORC1 mRNA Expression
M.J. Rieder et al. N Engl J Med 2005;352:


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