1. Distinct and Dynamic Requirements for mTOR Signaling in Hematopoiesis and Leukemogenesis 
Alex Kentsis, A. Thomas Look 
Cell Stem Cell 
Volume 11, Issue 3, Pages (September 2012)
DOI: /j.stem
Copyright © 2012 Elsevier Inc. Terms and Conditions

2. Figure 1
Contribution of mTORC1 and mTORC2 Signaling to Normal Hematopoiesis and PTEN Loss-Induced Leukemogenesis
PTEN negatively regulates PI3K-AKT signaling, which is mediated in part by mTORC1 and mTORC2, multiprotein complexes containing the mTOR kinase and specific substrate recruitment factors Raptor and Rictor, respectively.
Cell Stem Cell  , DOI: ( /j.stem )
Copyright © 2012 Elsevier Inc. Terms and Conditions