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Systemic and local effects following intra-articular injection of FX006, an extended release, PLGA microsphere formulation of triamcinolone acetonide: results from two nonclinical toxicity studies in dogs T.L. Williamson, A. Walz, D. Garlick, R. Lightfoot-Dunn, K. Schafer, S. Kelley, N. Bodick Osteoarthritis and Cartilage Volume 25, Pages S431-S432 (April 2017) DOI: /j.joca Copyright © Terms and Conditions
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Figure 1 Blank PLGA microsphere synovial localization and FBR 4 weeks post injection (H&E). A) Localization of blank PLGA microspheres (arrow) across the synovium (double head arrow). 4x objective magnification.B) FBR consisting of macrophages (arrows) and multinucleated giant cells (arrowhead) associated with microspheres (asterisk). 40x objective magnification. Osteoarthritis and Cartilage , S431-S432DOI: ( /j.joca ) Copyright © Terms and Conditions
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