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Kinase signaling and targeted therapy for primary myelofibrosis

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Presentation on theme: "Kinase signaling and targeted therapy for primary myelofibrosis"— Presentation transcript:

1 Kinase signaling and targeted therapy for primary myelofibrosis
Qiong Yang, John D. Crispino, Qiang Jeremy Wen  Experimental Hematology  Volume 48, Pages (April 2017) DOI: /j.exphem Copyright © 2016 ISEH - International Society for Experimental Hematology Terms and Conditions

2 Figure 1 Important pathways in the development of megakaryocytes. Aurora A kinase, JAK-STAT, and RhoA/ROCK are important pathways regulating the proliferation, survival, differentiation, enomitosis, and proplatelet formation of megakaryocytes. Mutations of proteins are indicated by stars. Experimental Hematology  , 32-38DOI: ( /j.exphem ) Copyright © 2016 ISEH - International Society for Experimental Hematology Terms and Conditions


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