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Jason B. Price, MD, Adnan Divjan, William R. Montfort, PhD, Kirstie H

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Presentation on theme: "Jason B. Price, MD, Adnan Divjan, William R. Montfort, PhD, Kirstie H"— Presentation transcript:

1 IgE against bed bug (Cimex lectularius) allergens is common among adults bitten by bed bugs 
Jason B. Price, MD, Adnan Divjan, William R. Montfort, PhD, Kirstie H. Stansfield, MA, PhD, Greg A. Freyer, PhD, Matthew S. Perzanowski, PhD  Journal of Allergy and Clinical Immunology  Volume 129, Issue 3, Pages e2 (March 2012) DOI: /j.jaci Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Concentrations of IgE antibodies against C lectularius extract, C lectularius nitrophorin recombinant protein, Dermataphagoides farinae, and German cockroach among the 30 adults reporting bed bug bites in the past year. Absence of a bar indicates that the subject had undetectable IgE levels (ie, <0.1 IU/mL). Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Western blot of human (subject 23) IgE binding to cNP and C lectularius extract. cNP is a 32-kDa protein. A similar sized band can be seen in the extract. The slight difference in size likely is due to posttranslational modifications of the cNP. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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