1. Volume 75, Issue 9, Pages 880-881 (May 2009)
Phosphate: despite advances in research, the benefits to patients remain limited 
Marc E. De Broe 
Kidney International 
Volume 75, Issue 9, Pages (May 2009)
DOI: /ki
Copyright © 2009 International Society of Nephrology Terms and Conditions

2. Figure 1
Phosphorus-induced alterations in calcium and/or vitamin D metabolism change parathyroid gland function in chronic kidney disease. 1, CASR: cell suface G protein–coupled receptor of extracellular ionized Ca2+; 2, vitamin D receptor: nuclear receptor controlling gene transcription; 3, putative phosphate sensor; 4, FGF23 is a negative regulator of parathyroid function.
Adapted from Quarles.3
Kidney International  , DOI: ( /ki )
Copyright © 2009 International Society of Nephrology Terms and Conditions