1. Nifty Alleles, a Plethora of Interactions, and Imagination Advance Understanding of Smc5/6’s Roles with Chromosomes 
Rachel E. Langston, Ted Weinert 
Molecular Cell 
Volume 60, Issue 6, Pages (December 2015)
DOI: /j.molcel
Copyright © 2015 Elsevier Inc. Terms and Conditions

2. Figure 1
Model Describing Smc5/6’s Role in Fork Stabilization at Pausing Sites and Recombination Intermediate Resolution
(A) Cartoon representation of the Smc5/6 complex.
(B) Model of Smc5/6’s role in G2. Menolfi et al. propose that Smc5/6 is both stabilizing/resolving the stalled replication fork at natural pause sites and working in a parallel pathway with Sgs1 to resolve recombination intermediates arising during post-replication repair. To unite the two roles of Smc5/6, we theorize that Smc5/6 could be preventing both the stalled replication fork and the recombination structure from resolving into another “toxic” intermediates (dashed lines).
Molecular Cell  , DOI: ( /j.molcel )
Copyright © 2015 Elsevier Inc. Terms and Conditions