1. Factors influencing the relationship between disease activity (as measured with the ASDAS) and radiographic progression (as measured with the 2-year mSASSS progression) and possible relationships between them (A) hypothesis 1: occupational activity modifies the relationship between disease activity and radiographic progression and this effect might be confounded by the effect of gender, smoking status and/or low socioeconomic status, which can, for example, be measured with education, personal income, family income.
Factors influencing the relationship between disease activity (as measured with the ASDAS) and radiographic progression (as measured with the 2-year mSASSS progression) and possible relationships between them (A) hypothesis 1: occupational activity modifies the relationship between disease activity and radiographic progression and this effect might be confounded by the effect of gender, smoking status and/or low socioeconomic status, which can, for example, be measured with education, personal income, family income. (B) Hypothesis 2: smoking status modifies the relationship between disease activity and radiographic progression and this effect might be confounded by the effect of gender, occupational activity and/or low socioeconomic status. ASDAS, Ankylosing Spondylitis Disease Activity Score; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score.
Sofia Ramiro et al. RMD Open 2015;1:e000153
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