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Volume 64, Issue 6, Pages (December 2003)

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Presentation on theme: "Volume 64, Issue 6, Pages (December 2003)"— Presentation transcript:

1 Volume 64, Issue 6, Pages 2100-2107 (December 2003)
Dietary flaxseed meal reduces proteinuria and ameliorates nephropathy in an animal model of type II diabetes mellitus  Manuel T. Velasquez, S.A.M. J. Bhathena, Tedine Ranich, Arnold M. Schwartz, David E. Kardon, A.L.I. A. Ali, Christian C. Haudenschild, Carl T. Hansen  Kidney International  Volume 64, Issue 6, Pages (December 2003) DOI: /j x Copyright © 2003 International Society of Nephrology Terms and Conditions

2 Figure 1 Representative light micrographs periodic acid-Schiff (PAS)-stained kidney sections from obese spontaneously hypertensive/NIH-corpulent (SHR/N-cp) rats fed with either casein (A), soy protein concentrate (B), or flaxseed meal (C) (×40). (A) Some glomeruli show increased PAS staining, whereas others are sclerotic. The tubulointerstitium shows foci of atrophic or dilated tubules, some filled with proteinaceous casts inside lumina and surrounded by mononuclear cell infiltrate, and, rarely, interstitial fibrosis. (B) Glomerular and tubulointerstitial lesions appear to be less prominent with soy protein concentrate feeding. (C) In contrast, glomerular and tubulointerstitial lesions are markedly reduced by flaxseed meal supplementation. Higher magnification (×200) shows essentially similar pattern of severity of lesions with casein (D), soy protein concentrate (E), or flaxseed meal (F). Kidney International  , DOI: ( /j x) Copyright © 2003 International Society of Nephrology Terms and Conditions


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