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Published byΙωάννα Τομαραίοι Modified over 5 years ago
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Fig. 3. Activation of MMCs and CTMCs after stimulation through FcεRI
Fig. 3. Activation of MMCs and CTMCs after stimulation through FcεRI. (A) Intracellular expression of phospho-Syk, (B) surface expression of CD107a, and (C) degranulation, measured as percentage of β-hexosaminidase secretion, in sensitized MMCs and CTMCs with mouse IgE or anti-DNP IgE after 30 minutes of activation with α-IgE or DNP-HSA. (D) Percentage of β-hexosaminidase secreted by MMCs and CTMCs after stimulation with compound 48/80. Data correspond to bone marrow-derived MCs obtained from Balb/c mice. MMC, mucosal mast cell; CTMC, connective tissue mast cell; IgE, immunoglobulin E; DNP, 2,4-dinitrophenol; DNP-HAS, dinitrophenylated human serum albumin; MC, mast cell. Fig. 3. Activation of MMCs and CTMCs after stimulation through FcεRI. (A) Intracellular expression of phospho-Syk, (B) surface expression of CD107a, and (C) degranulation, measured as percentage of β-hexosaminidase secretion, in sensitized MMCs and CTMCs with mouse IgE or anti-DNP IgE after 30 minutes of activation… Allergy Asthma Immunol Res May;10(3):
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